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Russian Journal of Human Reproduction ; 28(6):101-109, 2022.
Article in Russian | Scopus | ID: covidwho-2204280

ABSTRACT

The article conducts a study of the effect of new coronavirus infection (SARS-CoV-2) on the functional state of newborns born from women with a confirmed diagnosis of COVID-19 in the Stavropol region. Objective. To study the clinical and laboratory manifestations of SARS-CoV-2 in newborns born from women with a confirmed diagnosis of COVID-19 and women who suffered during pregnancy and recovered. Material and methods. A retrospective analysis of the diseases of 162 pregnant women hospitalized in the Stavropol region was carried out. The core of the study showed 81 women diagnosed with a new SARS-CoV-2 coronavirus infection. A retrospective analysis of cases of illness was carried out in 81 newborns born to women from the original group. Results. It was found that 52/81 (64.2%) women were delivered through the natural birth canal, 29/81 (35.8%) of the women in labor due to the increase in respiratory failure and, as a result, fetal hypoxia, were delivered by ACS. In 7/81 (8.64) children, according to pulse oximetry, the expected content of O2 in the blood was detected. In children, there is an increase in C-reactive protein and other inflammatory mediators with COVID-19, in contrast to large ones. They have extremely common leukopenia and lymphopenia. To a lesser extent, the concentration of the concentration of subpopulations of T-lymphocytes. Conclusion. In 2022, the existence of transmission of coronavirus from mother to fetus has not been proven. In this regard, the management of pregnant women should be individualized on the basis of taking into account obstetric indications, and the management of newborn children should be carried out, depending on the characteristics of the clinical case, together with pediatricians and, if necessary, with the staff of ICU. © 2022, Media Sphera Publishing Group. All rights reserved.

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